CRS/ICANS Unveiled: From Detection to Intervention
SELF STUDY / ENDURING - ESTIMATED TIME TO COMPLETE ACTIVITY: 25 Minutes
Overview
Participants will delve into advanced therapies in Chimeric Antigen Receptor (CAR) T-cell treatment, focusing on their ability to target specific antigens for cell activation and tumor cell eradication. The session will also address the complexities of managing Cytokine Release Syndrome (CRS) and Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS), the most common toxicities associated with CAR T-cell therapy, highlighting the challenges these conditions pose in patient care.
Target Audience
This CME initiative was designed for oncologists, surgeons, radiation oncologists, NPs, PAs, pharmacists, nurses, and other healthcare professionals involved in the treatment of patients with cancer.
Learning Objectives
1. Identify signs and symptoms of CRS/ICANS.
2. Review monitoring strategies for patients with CRS/ICANS
3. Discuss treatment and management options for CRS/ICANS.
Faculty
Alex Evans, PharmD, BCOP
Alexandra Evans is a clinical pharmacy specialist practicing in malignant hematology, bone marrow transplantation, and cellular therapies at the University of Cincinnati Medical Center. She received her Doctor of Pharmacy degree from the University of Cincinnati and then completed both her PGY1 Pharmacy Practice Residency and PGY2 Oncology Residency at the University of Cincinnati Medical Center. Her main areas of interest include acute leukemias, bone marrow transplantation, and coordinating complex care regimens for patients with malignant hematologic cancers.
Disclosures:
In accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education, Horizon CME (HCME) ensures that continuing education activities are balanced, independent, objective, and scientifically rigorous.
All persons in a position to influence the content of an accredited continuing education activity provided by Horizon CME are required to disclose to HCME any relevant financial relationships with ineligible companies within the past 24 months. All reported relevant financial relationships have been mitigated by Horizon CME.
Alex Evans, PharmD, BCOP discloses no relevant financial relationships with any entity producing, marketing, re-selling, or distributing healthcare goods or services consumed by, or used on, patients during the past 24 months.
Available Credit
- 0.50 AMA PRA Category 1 Credit™Horizon CME designates this Enduring activity for a maximum of 0.50 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
- 0.50 ANCCThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the American Nurses Credentialing Center’s Commission on Accreditation through the joint providership of the Nurse Practitioner Healthcare Foundation and Horizon CME. The Nurse Practitioner Healthcare Foundation is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation. NPHF is awarding the contact hours and is responsible for adherence to the ANCC criteria. Upon completion, NPs and RNs will be awarded up to 0.50 credit.
Price
There are no fees for participating and receiving CME credit for this enduring activity. To receive CME credit participants must:
- Read the CME/CE information and faculty disclosures.
- Participate in the online activity.
- Complete the post-test
- Submit the evaluation form
DISCLAIMER:
This activity is designed for educational purposes. Participants have a responsibility to utilize this information to enhance their professional development to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making before applying any information, whether provided here or by others, for any professional use.
Required Hardware/software
Access to the internet is required.
Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above
Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above